Droit Administratif Thai Style: A Comparative Analysis of the Administrative Courts in Thailand

A system of Administrative Courts was set up for the first time in Thailand as an important part of the new Thai Constitution of 1997. After dealing with issues raised in undertaking comparative analysis, this article traces the background to the introduction of the court, with particular reference to the strong influence of the French system of droit administratif in the development of the Council of State in Thailand, and in the conception of the current Thai system of administrative justice. The discussion proceeds to consider the institutional safeguards which were put in place to secure the independence of the Administrative Courts. The following sections deal with the characteristics of the court, which are mainly discussed in terms of its jurisdictional limits, the grounds set out for its intervention, the remedies it is able to award, and its work load. Finally, some of the court’s significant judgments are considered in the context of the current constitutional situation in Thailand

Back to Government? Reregulating British Railways

Back to Government?: The Pluralistic Deficit in the Decisionmaking Processes and Before the Courts, Symposium. University of Trento, Italy, June 11-12, 2004

Natural experiments: An overview of methods, approaches, and contributions to public health intervention research

Population health interventions are essential to reduce health inequalities and tackle other public health priorities, but they are not always amenable to experimental manipulation. Natural experiment (NE) approaches are attracting growing interest as a way of providing evidence in such circumstances. One key challenge in evaluating NEs is selective exposure to the intervention. Studies should be based on a clear theoretical understanding of the processes that determine exposure. Even if the observed effects are large and rapidly follow implementation, confidence in attributing these effects to the intervention can be improved by carefully considering alternative explanations. Causal inference can be strengthened by including additional design features alongside the principal method of effect estimation.NEstudies often rely on existing (including routinely collected) data. Investment in such data sources and the infrastructure for linking exposure and outcome data is essential if the potential for such studies to inform decision making is to be realized

Multilevel Modelling for Public Health and Health Services Research

This open access book is a practical introduction to multilevel modelling or multilevel analysis (MLA) – a statistical technique being increasingly used in public health and health services research. The authors begin with a compelling argument for the importance of researchers in these fields having an understanding of MLA to be able to judge not only the growing body of research that uses it, but also to recognise the limitations of research that did not use it. The volume also guides the analysis of real-life data sets by introducing and discussing the use of the multilevel modelling software MLwiN, the statistical package that is used with the example data sets. Importantly, the book also makes the training material accessible for download – not only the datasets analysed within the book, but also a freeware version of MLwiN to allow readers to work with these datasets. The book’s practical review of MLA comprises: Theoretical, conceptual, and methodological background Statistical background The modelling process and presentation of research Tutorials with example datasets Multilevel Modelling for Public Health and Health Services Research: Health in Context is a practical and timely resource for public health and health services researchers, statisticians interested in the relationships between contexts and behaviour, graduate students across these disciplines, and anyone interested in utilising multilevel modelling or multilevel analysis. “Leyland and Groenewegen’s wealth of teaching experience makes this book and its accompanying tutorials especially useful for a practical introduction to multilevel analysis.” ̶ Juan Merlo, Professor of Social Epidemiology, Lund University “Comprehensive and insightful. A must for anyone interested in the applications of multilevel modelling to population health”. ̶ S. (Subu) V. Subramanian, Professor of Population Health and Geography, Harvard University ; For researchers and students with a basic mastery of ordinary least squares and logistic regression Discusses multilevel analysis in context of public health, health services research, and epidemiology Includes an online component where users can download the datasets analyzed in the book, and also a freeware version of the multilevel modelling software MLwiN ​​​​​​​Can be used as part of a course on multilevel modelling, or as a self-training tex

How successful was the English teenage pregnancy strategy? Response to Wellings K, Palmer MJ, Gear RS et al. Changes in conceptions in women younger than 18 years and the circumstances of young mothers in England in 2000-12: an observational study

Kaye Wellings and colleagues' paper (Aug 6, p 586)1 and accompanying Comment2 ascribe the fall in teenage pregnancies in England since 1998 to the Teenage Pregnancy Strategy published in 1999. Unlike the interim assessment by the same authors,3 the paper draws no parallels with other UK countries, but a comparison with trends in conceptions among 15–17 year olds in Wales and Scotland raises questions about how far the fall can be attributed to the strategy (figure).4,

Examination of silver-graphite lithographically printed resistive strain sensors

This paper reports the design and manufacture of three differing types of resistive strain sensitive structures fabricated using the Conductive Lithographic Film (CLF) printing process. The structures, utilising two inks prepared with silver and graphite particulates as the conductive phase, have been analysed to determine electrical and mechanical properties with respect to strain, temperature and humidity when deposited on four alternative substrate materials (GlossArt, PolyArt, Teslin and Melinex)

Multilevel Modelling for Public Health and Health Services Research: Health in Context

This open access book is a practical introduction to multilevel modelling or multilevel analysis (MLA) – a statistical technique being increasingly used in public health and health services research. The authors begin with a compelling argument for the importance of researchers in these fields having an understanding of MLA to be able to judge not only the growing body of research that uses it, but also to recognise the limitations of research that did not use it. The volume also guides the analysis of real-life data sets by introducing and discussing the use of the multilevel modelling software MLwiN, the statistical package that is used with the example data sets. Importantly, the book also makes the training material accessible for download – not only the datasets analysed within the book, but also a freeware version of MLwiN to allow readers to work with these datasets. The book’s practical review of MLA comprises: Theoretical, conceptual, and methodological background, Statistical background, The modelling process and presentation of research, Tutorials with example datasets. Multilevel Modelling for Public Health and Health Services Research: Health in Context is a practical and timely resource for public health and health services researchers, statisticians interested in the relationships between contexts and behaviour, graduate students across these disciplines, and anyone interested in utilising multilevel modelling or multilevel analysis

CRACM/Orai ion channel expression and function in human lung mast cells

BackgroundInflux of extracellular Ca2+ into human lung mast cells (HLMCs) is essential for the FcεRI-dependent release of preformed granule-derived mediators and newly synthesized autacoids and cytokines. However, the identity of the ion channels underlying this Ca2+ influx is unknown. The recently discovered members of the CRACM/Orai ion channel family that carries the Ca2+ release–activated Ca2+ current are candidates.ObjectivesTo investigate the expression and function of CRACM channels in HLMCs.MethodsCRACM mRNA, protein, and functional expression were examined in purified HLMCs and isolated human bronchus.ResultsCRACM1, -2, and -3 mRNA transcripts and CRACM1 and -2 proteins were detectable in HLMCs. A CRACM-like current was detected following FcεRI-dependent HLMC activation and also in HLMCs dialyzed with 30 μM inositol triphosphate. The Ca2+-selective current obtained under both conditions was blocked by 10 μM La3+ and Gd3+, known blockers of CRACM channels, and 2 distinct and specific CRACM-channel blockers—GSK-7975A and Synta-66. Both blockers reduced FcεRI-dependent Ca2+ influx, and 3 μM GSK-7975A and Synta-66 reduced the release of histamine, leukotriene C4, and cytokines (IL-5/-8/-13 and TNFα) by up to 50%. Synta-66 also inhibited allergen-dependent bronchial smooth muscle contraction in ex vivo tissue.ConclusionsThe presence of CRACM channels, a CRACM-like current, and functional inhibition of HLMC Ca2+ influx, mediator release, and allergen-induced bronchial smooth muscle contraction by CRACM-channel blockers supports a role for CRACM channels in FcεRI-dependent HLMC secretion. CRACM channels are therefore a potential therapeutic target in the treatment of asthma and related allergic diseases